Bilger A, Lambert PF. Rapid-onset cancer. Tumour Virus Res. 2025 Jun;19:200312. doi: 10.1016/j.tvr.2024.200312. Epub 2025 Jan 2. PMID: 39755235; PMCID: PMC11764593.
Loke ASW, Lambert PF, Spurgeon ME. Current In Vitro and In Vivo Models to Study MCPyV-Associated MCC. Viruses. 2022 Oct 7;14(10):2204. doi: 10.3390/v14102204. PMID: 36298759; PMCID: PMC9607385.
Wang W, Pope A, Ward-Shaw E, Buehler D, Bachelerie F, Lambert PF. Increased Susceptibility of WHIM Mice to Papillomavirus-induced Disease is Dependent upon Immune Cell Dysfunction. PLoS Pathog. 2024 Sep 3;20(9):e1012472. doi: 10.1371/journal.ppat.1012472. PMID: 39226327; PMCID: PMC11398641.
Torres AD, King RE, Uberoi A, Buehler D, Yoshida S, Ward-Shaw E, Lambert PF. Deficiency in Ever2 does not increase susceptibility of mice to pathogenesis by the mouse papillomavirus, MmuPV1. J Virol. 2024 Jul 23;98(7):e0017424. doi: 10.1128/jvi.00174-24. Epub 2024 Jun 13. PMID: 38869286; PMCID: PMC11265430.
Spurgeon ME, Townsend EC, Blaine-Sauer S, McGregor SM, Horswill M, den Boon JA, Ahlquist P, Kalan L, Lambert PF. Key aspects of papillomavirus infection influence the host cervicovaginal microbiome in a preclinical murine papillomavirus (MmuPV1) infection model. mBio. 2024 Jun 12;15(6):e0093324. doi: 10.1128/mbio.00933-24. Epub 2024 May 14. PMID: 38742830; PMCID: PMC11237646.
King RE, Rademacher J, Ward-Shaw ET, Hu R, Bilger A, Blaine-Sauer S, Spurgeon ME, Thibeault SL, Lambert PF. The Larynx is Protected from Secondary and Vertical Papillomavirus Infection in Immunocompetent Mice. Laryngoscope. 2024 May;134(5):2322-2330. doi: 10.1002/lary.31228. Epub 2023 Dec 12. PMID: 38084790; PMCID: PMC11006576.
Romero-Masters JC, Muehlbauer LK, Hayes M, Grace M, Shishkova E, Coon JJ, Munger K, Lambert PF. MmuPV1 E6 induces cell proliferation and other hallmarks of cancer. mBio. 2023 Dec 19;14(6):e0245823. doi: 10.1128/mbio.02458-23. Epub 2023 Oct 31. PMID: 37905801; PMCID: PMC10746199.
Romero-Masters JC, Grace M, Lee D, Lei J, DePamphilis M, Buehler D, Hu R, Ward-Shaw E, Blaine-Sauer S, Lavoie N, White EA, Munger K, Lambert PF. MmuPV1 E7’s interaction with PTPN14 delays Epithelial differentiation and contributes to virus-induced skin disease. PLoS Pathog. 2023 Apr 10;19(4):e1011215. doi: 10.1371/journal.ppat.1011215. PMID: 37036883; PMCID: PMC10085053.
Wang W, Spurgeon ME, Pope A, McGregor S, Ward-Shaw E, Gronski E, Lambert PF. Stress keratin 17 and estrogen support viral persistence and modulate the immune environment during cervicovaginal murine papillomavirus infection. Proc Natl Acad Sci U S A. 2023 Mar 21;120(12):e2214225120. doi: 10.1073/pnas.2214225120. Epub 2023 Mar 14. PMID: 36917668; PMCID: PMC10041145.
Romero-Masters JC, Lambert PF, Munger K. Molecular Mechanisms of MmuPV1 E6 and E7 and Implications for Human Disease. Viruses. 2022 Sep 28;14(10):2138. doi: 10.3390/v14102138. PMID: 36298698; PMCID: PMC9611894.
Moreno R, Buehler D, Lambert PF. MmuPV1-Induced Cutaneous Squamous Cell Carcinoma Arises Preferentially from Lgr5+ Epithelial Progenitor Cells. Viruses. 2022 Aug 11;14(8):1751. doi: 10.3390/v14081751. PMID: 36016373; PMCID: PMC9414603.
Blaine-Sauer S, Shin MK, Matkowskyj KA, Ward-Shaw E, Lambert PF. A Novel Model for Papillomavirus-Mediated Anal Disease and Cancer Using the Mouse Papillomavirus. mBio. 2021 Jul 20:e0161121. doi: 10.1128/mBio.01611-21. Epub ahead of print. PMID: 34281391.
Wei T, Choi S, Buehler D, Lee D, Ward-Shaw E, Anderson RA, Lambert PF. Role of IQGAP1 in Papillomavirus-Associated Head and Neck Tumorigenesis. Cancers (Basel). 2021 May 10;13(9):2276. doi: 10.3390/cancers13092276. PMID: 34068608; PMCID: PMC8126105.
Spurgeon ME, Liem A, Buehler D, Cheng J, DeCaprio JA, Lambert PF. The Merkel Cell Polyomavirus T Antigens Function as Tumor Promoters in Murine Skin. Cancers (Basel). 2021 Jan 9;13(2):222. doi: 10.3390/cancers13020222. PMID: 33435392; PMCID: PMC7827793.
Loke ASW, Longley BJ, Lambert PF, Spurgeon ME. A Novel In Vitro Culture Model System to Study Merkel Cell Polyomavirus-Associated MCC Using Three-Dimensional Organotypic Raft Equivalents of Human Skin. Viruses. 2021 Jan 19;13(1):138. doi: 10.3390/v13010138. PMID: 33478104; PMCID: PMC7835998.
Wei T, Buehler D, Ward-Shaw E, Lambert PF. An Infection-Based Murine Model for Papillomavirus-Associated Head and Neck Cancer. mBio. 2020;11(3):e00908-20. Published 2020 May 12. doi:10.1128/mBio.00908-20
Bilger A, King RE, Schroeder JP, et al. A Mouse Model of Oropharyngeal Papillomavirus-Induced Neoplasia Using Novel Tools for Infection and Nasal Anesthesia. Viruses. 2020;12(4):E450. Published 2020 Apr 16. doi:10.3390/v12040450
Wei T, Choi S, Buehler D, Anderson RA, Lambert PF. A PI3K/AKT Scaffolding Protein, IQ Motif-Containing GTPase Associating Protein 1 (IQGAP1), Promotes Head and Neck Carcinogenesis. Clin Cancer Res. 2020;26(1):301‐311. doi:10.1158/1078-0432.CCR-19-1063
Spurgeon ME, Lambert PF. Mus musculus Papillomavirus 1: a New Frontier in Animal Models of Papillomavirus Pathogenesis. J Virol. 2020;94(9):e00002-20. Published 2020 Apr 16. doi:10.1128/JVI.00002-20
Wang W, Uberoi A, Spurgeon M, et al. Stress keratin 17 enhances papillomavirus infection-induced disease by downregulating T cell recruitment. PLoS Pathog. 2020;16(1):e1008206. Published 2020 Jan 22. doi:10.1371/journal.ppat.1008206
Torres AD, Spurgeon ME, Bilger A, et al. The human papillomavirus 16 E5 gene potentiates MmuPV1-Dependent pathogenesis. Virology. 2020;541:1‐12. doi:10.1016/j.virol.2019.12.002
Spurgeon ME, Lambert PF. Sexual transmission of murine papillomavirus (MmuPV1) in Mus musculus. Elife. 2019;8:e50056. Published 2019 Oct 17. doi:10.7554/eLife.50056
Spurgeon ME, Uberoi A, McGregor SM, Wei T, Ward-Shaw E, Lambert PF. A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract. mBio. 2019;10(2):e00180-19. Published 2019 Mar 5. doi:10.1128/mBio.00180-19
Shin MK, Payne S, Bilger A, et al. Activating Mutations in Pik3caContribute to Anal Carcinogenesis in the Presence or Absence of HPV-16 Oncogenes. Clin Cancer Res. 2019;25(6):1889‐1900. doi:10.1158/1078-0432.CCR-18-2843
Nyman PE, Buehler D, Lambert PF. Loss of Function of Canonical Notch Signaling Drives Head and Neck Carcinogenesis. Clin Cancer Res. 2018;24(24):6308‐6318. doi:10.1158/1078-0432.CCR-17-3535
Uberoi A, Yoshida S, Lambert PF. Development of an in vivo infection model to study Mouse papillomavirus-1 (MmuPV1). J Virol Methods. 2018;253:11‐17. doi:10.1016/j.jviromet.2017.12.002
Spurgeon ME, den Boon JA, Horswill M, et al. Human papillomavirus oncogenes reprogram the cervical cancer microenvironment independently of and synergistically with estrogen. Proc Natl Acad Sci U S A. 2017;114(43):E9076‐E9085. doi:10.1073/pnas.1712018114
Uberoi A, Yoshida S, Frazer IH, Pitot HC, Lambert PF. Role of Ultraviolet Radiation in Papillomavirus-Induced Disease. PLoS Pathog. 2016;12(5):e1005664. Published 2016 May 31. doi:10.1371/journal.ppat.1005664
Park S, Park JW, Pitot HC, Lambert PF. Loss of Dependence on Continued Expression of the Human Papillomavirus 16 E7 Oncogene in Cervical Cancers and Precancerous Lesions Arising in Fanconi Anemia Pathway-Deficient Mice. mBio. 2016;7(3):e00628-16. Published 2016 May 17. doi:10.1128/mBio.00628-16
Makielski KR, Lee D, Lorenz LD, et al. Human papillomavirus promotes Epstein-Barr virus maintenance and lytic reactivation in immortalized oral keratinocytes. Virology. 2016;495:52‐62. doi:10.1016/j.virol.2016.05.005